发明名称 Imidazoline derivatives.
摘要 Compounds of formula (I): <CHEM> wherein R<1> is halogen, alkyl or alkoxy; R<2> is hydrogen, halogen, alkyl or alkoxy; R<3> is an optionally substituted, saturated, unsaturated or aromatic, carbo- or hetero-, mono- or bi-cyclic group; R<4> is hydrogen or alkyl, -@@ (CH2)n - R<3> is located meta or para to the imidazolinylamino group; one of R<5> and R<6> is hydrogen and the other is hydrogen, alkyl or acyl; and N is 0, 1, 2 or 3, or an acid addition salt thereof, have antidiarrhoeal activity.
申请公布号 EP0070084(A2) 申请公布日期 1983.01.19
申请号 EP19820302004 申请日期 1982.04.20
申请人 BEECHAM GROUP PLC 发明人 BAKER, GEOFFREY HAROLD;BEELEY, LEE JAMES;NEWSOME, PETER MARTIN;RICHARDS, DAVID HUGH
分类号 A61K31/415;A61P1/12;A61P9/00;A61P9/12;A61P25/02;A61P25/20;C07D233/50;C07D405/12;C07D409/12;(IPC1-7):C07D233/50;A61K31/41 主分类号 A61K31/415
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