| 摘要 |
Antiviral compositions and use thereof which contain as active component aminosulfonylhalogenobenzoic acid derivatives of the formula: <CHEM> wherein X and Y, independently of each other, denote hydrogen atom, fluorine atom, chlorine atom, bromine atom, amino group or nitro group, R1 denotes hydrogen atom or lower alkyl group, R2 denotes hydrogen atom, amino group, lower alkyl group, hydroxyalkyl group, lower alkoxy group, aryl group, guanyl group, guanidino group, ureido group, oxamoylamino group or chloro-substituted pyridazinoamino group, or R1 and R2 together with the nitrogen atom in the formula (I) may form a saturated heterocyclic group having 4 or 5 carbon atoms, in which the carbon atoms may be substituted by and oxygen atom or nonsubstituted or lower alkyl group-substituted nitrogen atom, and R3 denotes hydrogen atom, cyclohexyl group, benzyl group, aryl group, or straight or branched alkyl group which consists of 1 to 12 carbon atoms, provided that 3-aminosulfonyl-4-halogenobenzoic acid is excluded from the compositions; or the salts thereof. They are effective for therapeutic treatment of various infectious diseases which are caused from viruses, for example, upper respiratory infection, pneumonia, Bronchitis and so on.
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