KIRURGISKT SJELVUPPLOSANDE SUTURMATERIAL AV KOMPLEXA MONOKARBOXYLCELLULOSA-METALL-LIGAND- FORENINGAR OCH FORFARANDE FOR FRAMSTELLNING DERAV

摘要

An absorbable surgical suture material based on monocarboxycellulose having the general formula +TR where: m is a degree of polymerization of the initial cellulose from 250 to 3,300; p is a molar fraction of D-glucopyranose cycles in one polymer period from 0.95 to 0.05; q is a molar fraction of cycles of d-anhydroglucuronic acid from 0.05 to 0.95; S is a molar fraction of the complex fragment of D-anhydroglucuronic acid, metal, and ligand from 0.03 to 0.55; Me is a transition metal; n is a valence of the transition metal; k is a coordination number of the transition metal >/=4; Lig is polydentate ligands; Dent is a dentation of the ligands >/=2. A method for producing said material consists in that cellulose threads are first threaded with nitrogen oxides, then for 0.5 to 2.0 hours treated with a 0.5-2.0-percent solution of a salt of a transition metal with a coordination number not less than 4 in a suitable solvent, and after this treated for 0.5 to 2.0 hours with a 1.0-2.0-percent solution of a polydentate complexing agent in a suitable solvent.