| 摘要 |
<p>Novel benzothiopyran derivatives of the general formula in which R is free, esterified or amidated carboxyl or free or etherified hydroxymethyl, Ph is 1,2-phenylene which contains the group R-CO-NR3- and can be substituted, X is a group of the formula -CO-CR1=CR2, in which R1 and R2 independently of one another are hydrogen, acyl or a substituted or unsubstituted hydrocarbon radical or a heteroanalogue thereof or together are 3-membered to 5-membered lower alkylene, and R2 can also be free or etherified hydroxyl or hydroxyl esterified by an organic carboxylic aicd, and R3 is hydrogen or lower alkyl, possess antiallergic properties and can be used as medicaments. They are prepared, for example, by reacting a compound of the general formula (II) in which Ph, R3 and X are as defined, or a salt thereof, with one equivalent of an oxalic acid, which can be functionally modified, or a salt thereof.</p> |
