| 摘要 |
Guanidines of the general formula II <IMAGE> in which the substituents are defined in Claim 1, and their pharmaceutically acceptable salts are obtained by treating thienamycin (I) with a urea derivative, with intermediate protection of the oxygen functions and/or the carboxyl function, and converting compounds which may be obtained into their pharmaceutically acceptable salts. The novel compounds which can be prepared according to the invention are novel useful antibiotics which as a rule are active against various gram-positive and gram-negative bacteria and which are therefore used in human and veterinary medicine.
|
