| 摘要 |
Preventive as well as therapeutic treatment to alleviate the symptoms of skin disorders associated with disturbed keratinization or inflammation with one or more alpha or beta hydroxy-acids and alpha or beta ketoacids is disclosed. The alpha or beta hydroxyacids and alpha or beta ketoacids of this invention include free acids, or peroxide, amide, lactone, anhydride, ester, polymer, organic or inorganic salt forms thereof. Therapeutic compositions of this invention may include one or more of the alpha or beta hydroxyacids or the alpha or beta ketoacids of this invention present in a total amount of from 0.1 to 40 percent in an acceptable vehicle. The compositions are particularly useful for the topical treatment of skin conditions such as dry skin, ichthyosis, palmar and plantar hyperkeratosis, dandruff, Darier's disease, lichen simplex chronicus, keratoses, acne, psoriasis, eczema, pruritus and possibly warts and herpes.
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