发明名称 |
Cyclic ether vitamin d3 compounds, 1alpha (oh) 3-epi-vitamin d3 compounds and uses thereof |
摘要 |
Novel cyclic ether vitamin D3 compounds having a cyclic ether side chain are disclosed. These compounds were first identified as metabolites of 3-epi vitamin D3 produced via a tissue-specific metabolic pathway which catalyzes the formation of a cyclic ether structure. Also disclosed are 1 alpha (OH) 3-epi vitamin D3 compounds, which are produced via the epimerization of a 3- beta -hydroxyl group of 1 alpha (OH) vitamin D3 precursor in vivo. The vitamin D3 compounds of the present invention can be used as substitutes for natural and synthetic vitamin D3 compounds. |
申请公布号 |
AU7493698(A) |
申请公布日期 |
1998.12.08 |
申请号 |
AU19980074936 |
申请日期 |
1998.05.15 |
申请人 |
WOMEN & INFANT'S HOSPITAL |
发明人 |
SATAYANARAYANA G. REDDY |
分类号 |
A61K31/045;A61K31/351;A61P3/00;A61P3/02;A61P3/14;A61P5/18;A61P17/00;A61P19/08;A61P19/10;A61P43/00;C07C401/00;C07D303/14;C07D307/33;C07D309/04;C07D309/06 |
主分类号 |
A61K31/045 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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