PROCESS FOR PREPARING ESTERASTHINE AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH ACTIVE SUBSTANCES
摘要
<p>A new physiologically active substance named esterastin is now provided, which inhibits the activity of esterase and is useful as an immunosuppressive drug. Esterastin is produced by cultivating a micro-organism Streptomyces MD4-C1 identified as FERM-P 3723 or ATCC. 31336 in a culture medium under aerobic conditions and recovering it from the resulting culture. Esterastin is the compound having the formula CH3(CH2)4CHCHCH2CH +TR <IMAGE></p>