发明名称 Substituted chromans
摘要 The invention relates to chroman derivatives of the general formula <IMAGE> wherein R1 is hydrogen, lower alkyl, substituted phenyl, phenyl, phenyl-lower alkyl, substituted phenyl-lower alkyl or lower alkyl-amino-lower alkyl; R2 is <IMAGE> <IMAGE> <IMAGE> <IMAGE> R3, R4, R5 and R6 each is independently selected from hydrogen, hydroxy, amino, -o-acyl, -o-lower alkyl; <IMAGE> halogen, lower alkyl, or halo substituted lower alkyl; and salts and hydrates thereof. These compounds are useful as anti-inflammatory agents; for inhibition of blood platelet aggregation, as antiallergy and as antihypertensive agents.
申请公布号 US4360532(A) 申请公布日期 1982.11.23
申请号 US19810305304 申请日期 1981.09.24
申请人 E. R. SQUIBB & SONS, INC. 发明人 SUNDEEN, JOSEPH E.
分类号 C07D211/22;C07D211/26;C07D211/32;C07D311/58;C07D311/60;C07D311/64;(IPC1-7):C07D311/74;A61K31/35 主分类号 C07D211/22
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