发明名称 14-METHOXYMORPHINAN-6-ONE COMPOUNDS
摘要 <p>Docket No. 11861 14- METHOXYMOXYMORPHINAN-6-ONE COMPOUNDS Disclosed are 14-methoxy substituted 3-hydroxy or 3-methoxy -6-one morphinans characterized by the structural formula: wherein R is H or methyl; R1 is H, .alpha. methyl or .beta. methyl; and R2 is cyclobutylmethyl, cyclopropylmethyl, tetrahydrofurfuryl or dimethylallyl. The compounds of the present invention are variously useful as analgesics, narcotic antagonists and mixed analgesics /narcotic antagonists.</p>
申请公布号 CA1136130(A) 申请公布日期 1982.11.23
申请号 CA19800344573 申请日期 1980.01.29
申请人 SISA, INCORPORATED 发明人 RAZDAN, RAJ K.;GHOSH, ANIL C.
分类号 A61K31/47;A61P25/04;C07D221/28;C07D405/06;(IPC1-7):C07D405/06 主分类号 A61K31/47
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