发明名称 |
CHLOROBENZYL PHENOXY ALKOXYLIC COMPOUNDS |
摘要 |
<p>Compounds of formula (I) (I) wherein R1 and R2 are the same or different lower alkyls, R3 is hydrogen, a lower alkyl optionally substituted with pyridylmethyl or an ion of a pharmaceutically acceptable metal, and R4 is hydrogen or nitro; and the acid addition salts of said formula (I) compounds with pharmaceutically acceptable acids when R3 is pyridylmethyl. When R4 is nitro, R3 and/or R2 may also represent hydrogen. These compounds are useful in the treatment of hypercholesterolemia and hyperlipldemia because of their high effectiveness in reducing the level of cholesterol and lipids in the blood combined with very low general toxicitles and substantially reduced hepatomegalitic effects.</p> |
申请公布号 |
CA1136146(A) |
申请公布日期 |
1982.11.23 |
申请号 |
CA19800343753 |
申请日期 |
1980.01.16 |
申请人 |
SIEGFRIED AKTIENGESELLSCHAFT |
发明人 |
THIELE, KURT;AHMED, QUAZI;ADRIAN, RUDOLF;JAHN, ULRICH |
分类号 |
C07C69/712;A61K31/19;A61K31/195;A61K31/215;A61K31/22;A61K31/44;A61K31/4406;A61K31/4418;A61P3/06;C07C51/00;C07C59/125;C07C59/68;C07C67/00;C07C69/612;C07C201/00;C07C205/37;C07D213/30;(IPC1-7):07C59/70;07C69/712;07D213/30 |
主分类号 |
C07C69/712 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|