发明名称 |
ELLIPTICINES SUBSTITUTED IN POSITION 1 BY A POLYAMINE CHAIN, THEIR SYNTHESIS AND MEDICINES CONTAINING THEM |
摘要 |
<p>The novel derivatives correspond to the general formula: <IMAGE> (I) in which R1 is a Y-(CH2)n -NR4R5 group, where Y represents a single bond or the group <IMAGE> R4 and R5, identical or different, are hydrogen or an alkyl radical, preferably a lower alkyl, or again form together a ring which can include heteroatoms, in particular nitrogen atoms. n is a number ranging from 1 to 10, notably from 2 to 7, R2 is a hydrogen atom, a lower alkyl group or an aralkyl group in which the alkyl substituent is a lower alkyl group, and R3 is a hydrogen atom or a CH3 group useful for the treatment of leukemias.</p> |
申请公布号 |
EP0010029(B1) |
申请公布日期 |
1982.11.17 |
申请号 |
EP19790400666 |
申请日期 |
1979.09.19 |
申请人 |
ANVAR AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE |
发明人 |
BISAGNI, EMILE;DUCROCQ, CLAIRE;RIVALLE, CHRISTIAN;TAMBOURIN, PIERRE;WENDLING, FRANCOISE;CIVIER, ALAIN;MONTAGNIER, LUC;CHERMANN, JEAN-CLAUDE;GRUEST, JACQUELINE;LIDEREAU, ROSETTE |
分类号 |
A61K31/435;A61K31/44;A61K31/475;A61K31/495;A61P35/00;A61P35/02;C07D209/86;C07D209/88;C07D471/04;(IPC1-7):61K31/475;07D471/04 |
主分类号 |
A61K31/435 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|