| 摘要 |
PURPOSE:To obtain a safe composition for oral cavity, having excellent effects on prevention and treatment of periodontal diseases such as periodontitis, pyorrhea alveolaris, etc., containing musizin as an active ingredient. CONSTITUTION:A composition for oral cavity having effects on periodontal diseases of almost all symptoms, especially effective for preventing and treating periodontitis and pyorrhea alveolaris, containing 0.001-5.0wt%., preferably 0.005-0.5wt% calculated as active ingredient of musizin shown by the formula obtained by synthesis or extraction from the natural world (e.g. one from Rumex japonicus Houtt., perennial polygonaceous plant naturally growing in wet lands of each part of Japan). The composition is further blended with any of other drugs for alleviating periodontal diseases to raise effects synergistically. Although musizin is a little unstable to light rays, musizin can be stably added to the composition by liposome formation, etc., and raise mucosa absorption. Further the root of Rumex japonicus Houtt, is useful as a drug for skin disease and laxative and musizin has extremely high safety. |
