发明名称 |
1-SUBSTITUTED-3,4-EPOXYPYRROLIDINES |
摘要 |
<p>3,4-Epoxypyrrolidines substituted in the 1-position with alkyl, cycloalkyl and phenylalkyl are disclosed which have pharmaceutical application in cataract prevention in animals and as intermediates in preparation of trans-3-aryloxy-4-hydroxypyrrolidines. The epoxypyrrolidines are prepared by a novel route involving chlorination of pyrrolines in aqueous medium.</p> |
申请公布号 |
CA1135701(A) |
申请公布日期 |
1982.11.16 |
申请号 |
CA19800343329 |
申请日期 |
1980.01.09 |
申请人 |
ROBINS (A.H.) COMPANY, INC. |
发明人 |
WALSH, DAVID A.;WELSTEAD, WILLIAM J., JR. |
分类号 |
A61K31/40;A61P3/02;A61P3/08;A61P3/10;A61P27/02;C07D207/20;C07D491/04;C07D491/044;(IPC1-7):C07D491/044 |
主分类号 |
A61K31/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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