Method for racemate splitting of 2-hydroxypropionic acids

摘要

Process for the racemate resolution of 2-hydroxypropionic acids by reacting the racemic acid with an optically active base and subsequently separating off a diastereomeric salt of acid and base wherein 1-(4-chlorophenyl)ethylamine is used as the optically active base. A preferred embodiment is the racemate resolution of 2-hydroxy-3-methoxy-3,3-diphenylpropionic acid or 2-hydroxy-3-methyl-3,3-diphenylpropionic acid.