发明名称 |
Nicotinic derivatives of glucosamine and related pharmaceutical compositions |
摘要 |
The nicotinic derivatives of glucosamine, particularly N-nicotinoyl-glucosamine tetranicotinate are described as having anti-lipolitic, hypocholesterolemizing and antiaterogenic activities, at an equal or higher level than those of nicotinic acid, without the objectionable side effects shown by the acid. To prepare the compounds of the invention, nicotinoyl chloride hydrochloride and glucosamine hydrochloride are reacted in an organic solvent at a temperature of between 40 DEG C. and 120 DEG C.
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申请公布号 |
US4358441(A) |
申请公布日期 |
1982.11.09 |
申请号 |
US19810265348 |
申请日期 |
1981.05.19 |
申请人 |
LABORATORIO GUIDOTTI & C. S.P.A. |
发明人 |
MURMANN, WALTER;PONCHIROLI, OSVALDO |
分类号 |
A61K31/70;A61K31/7024;A61P3/06;C07H13/10;(IPC1-7):A61K31/70;C07H5/06 |
主分类号 |
A61K31/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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