发明名称 POLYSACCHARIDE PS-C FROM PLANT OF GENUS EPIMEDIUM, ITS PREPARATION, AND IMMUNE ENHANCER COMPRISING POLYSACCHARIDE PS-C AS ACTIVE INGREDIENT
摘要 PURPOSE:To obtain the titled drug capable of promoting the function of a chemotherapeutical drug by medicating the titled drug and the chemotherapeutical drug, etc. to a patient with reduced immune function, by comprising a polysaccharide PS-C which is extracted from a plant of the genus epimedium, isolated and purified, as an active ingredient. CONSTITUTION:A mixed solvent of water and an organic solvent (e.g., lower alcohol, etc.) compatible with water is added to a plant of the genus epimedium to give an aqueous extracted solution. An organic solvent compatible with water in any ratio is added to the solution to give a precipitate, which is dissolved in water. A long-chain quaternary ammonium salt is added to the solution, formed compounded substances are removed, the solution is purified by chromatography, etc., to give the desired fraction. Elemental analysis: C 40.75, H 6.28, ash trace amount. Molecular weight: 25,000+ or -15,000. Properties of substance: white slightly brown amorphous powder. Decomposition point: 175 deg.C pH: 7.0. Constitutional saccharide: found to have physical and chemical properties of arabinose, galactose, etc., and immnue enhancing action.
申请公布号 JPS57181018(A) 申请公布日期 1982.11.08
申请号 JP19810065893 申请日期 1981.04.30
申请人 ZENYAKU KOGYO KK 发明人 MIHASHI SUSUMU;TAKASE MUNEAKI;YASUI SOUSUKE;WASHISAWA TOMOO;YOSHIOKA KIMITOMO
分类号 A61K36/29;A61P37/04 主分类号 A61K36/29
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