| 发明名称 |
PYRAZOLES AND METHODS OF MAKING AND USING THE SAME |
| 摘要 |
The invention is based on the discovery that compounds of formula I possess unexpectedly high affinity for Alk 5 and/or Alk 4, and can be useful as antagonists thereof for preventing and/or treating numerous diseases, including fibrotic disorders. In one embodiment, the invention features a compound of formula I (I).
|
| 申请公布号 |
RS20050616(A) |
申请公布日期 |
2007.09.21 |
| 申请号 |
YUP20050616 |
申请日期 |
2004.02.12 |
| 申请人 |
BIOGEN IDEC MA INC. |
发明人 |
LEE WEN CHERNG;SUN LIHONG;SHAN FENG;CHUAQUI CLAUDIO;CORNEBISE MARK;PONTZ TIMOTHY;CARTER MARYBETH;SINGH JUSWINDER;BORIACK SJODIN PAULA ANN;LING LEONA;PETTER RUSSELL |
| 分类号 |
A01N43/58;A01N43/40;A01N43/42;A01N43/60;A61K31/44;A61K31/4427;A61K31/47;A61K31/495;A61K31/4965;A61K31/497;A61K31/50;A61K31/501;A61K31/54;A61P35/00;C07D;C07D401/04;C07D401/14;C07D405/14;C07D407/14;C07D413/14;C07D471/04 |
主分类号 |
A01N43/58 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
