| 摘要 |
1H-Tetrazole derivatives of the formula: <IMAGE> and pharmaceutically acceptable salts thereof, wherein the ring P is pyridine ring; A is carbonyl, methylene or C2-4 alkylidene; Y is oxygen, sulfur or -N(R1)- wherein R1 is hydrogen or C1-4 alkyl; each of X1 and X2 is hydrogen, halogen, C1-4 alkyl, C1-4 alkoxy, phenyl or substituted phenyl, any substitutent on the phenyl being halogen, C1-4 alkyl, C1-4 alkoxy or trifluoromethy; and R is hydrogen, C1-4 alkyl, C2-4 alkenyl, C2-4 alkynyl, hydroxy-C1-4 alkyl, C1-4 alkoxy-C1-4 alkyl, carboxy-C1-4 alkyl, C1-4 alkoxycarbonyl-C1-4 alkyl or substituted or unsubstituted amino-C1-4 alkyl, any substituted amino being C1-4 alkyl- or di-C1-4 alkyl-amino, piperidino, 1-pyrrolidinyl, morpholino, 1-piperazinyl and 4-C1-4 alkyl-1-piperazinyl; are useful as antiallergic agents. |
