发明名称 Production of immune interferon and its mRNA.
摘要 <p>Process for the production of IFN- gamma comprising incubating for a period of time at least sufficient for the production of IFN- gamma , a viable cell suspension which includes (a) leukocytes, (b) an inducer for production of IFN- gamma , and (c) a modulator for said inducer selected from the group consisting of mezerein and 12, 13-phorbol butyrate, said inducer and said modulator being present in said suspension in amounts sufficient to stimulate production of IFN- gamma ; process for producing homogeneous IFN- gamma ; process for producing IFN- gamma mRNA; and cloning process for production of IFN- @. Products disclosed are homogeneous IFN- gamma and its 2 species; and the host cells containing the recombinant cloning vehicle containing DNA segment coding for IFN- gamma .</p>
申请公布号 EP0063482(A2) 申请公布日期 1982.10.27
申请号 EP19820301961 申请日期 1982.04.16
申请人 MELOY LABORATORIES, INC. 发明人 BRAUDE, IRWIN ALLEN, DR.
分类号 A61K38/00;C07K14/57;(IPC1-7):12P21/00;12N15/00;07G7/00 主分类号 A61K38/00
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