| 摘要 |
PURPOSE:To obtain an antitumor agent, containing a saponin component of Tabebuia avellanedae Lorenz as an active substance and having cellulicidal effect. CONSTITUTION:An antitumor agent containing a saponin component present in bark of Tabebuia avellanedae Lorenz which is a deciduous leaved arbor of the family Bignonbiaceae as an active ingredient. The saponin component is obtained, e.g. by finely cutting bark, extracting the finely cut bark with a lower aliphatic alcohol, concentrating the resultant extract solution to give an extracted essence, dissolving the essence in n-butanol saturated with water, adding water, thoroughly shaking the mixture, allowing the mixture to stand, separating the n-butanol layer, removing saccharides and pigments together with water and evaporating the n-butanol layer to dryness. The resultant substance substantially contains the saponin component, which can be used as the active ingredient.
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