发明名称 Beta-lactamase inhibiting 2-beta-substituted-2-alpha-methyl-(5R)penam-3-alpha-carboxylic acid 1,1-dioxides and intermediates therefor
摘要 Beta-lactamase inhibiting 2-beta-substituted-2-alpha-methyl-(5R)penam-3-alpha-carboxylic acid 1,1-dioxides and esters thereof, wherein the 2-beta-substituent is cyano, acetyl, alkoxycarbonyl, omegahydroxyalkoxycarbonyl, carbalkoxymethoxycarbonyl or dialkylaminocarbonyl; intermediates therefor wherein the 2-beta-substituent is carboxy, chlorocarbonyl or aminocarbonyl; methods for their preparation and use as beta-lactamase inhibitors.
申请公布号 US4356174(A) 申请公布日期 1982.10.26
申请号 US19810301995 申请日期 1981.09.14
申请人 PFIZER INC. 发明人 BARTH, WAYNE E.
分类号 C07D499/897;A61K31/425;A61K31/43;A61P31/04;A61P43/00;C07D499/00;C07D499/04;C07D499/28;C07D499/32;C07D499/86;C07D499/87;C07D499/893;C07D519/06;(IPC1-7):A61K31/43;A61K31/42;C07D499/68;C07D513/04 主分类号 C07D499/897
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