发明名称 |
THIOCARNITINE DERIVATIVE, MANUFACTURE AND REMEDY FOR POISONING, HEPATIC DYSFUNCTION AND BURN |
摘要 |
A novel class of carnitine derivatives is disclosed which comprises thiocarnitine and the S-acyl thiocarnitines wherein the acyl radical is the radical of saturated organic acids having from 2 to 10 carbon atoms. The S-acyl thiocarnitines are prepared e.g. by reacting crotonoyl betaine halogenide with the corresponding thio-acid, while thiocarnitine is obtained by hydrolysis of an S-acyl thiocarnitine. These compounds are useful therapeutic agents, e.g. for the treatment of intoxications, liver malfunctions and burns. |
申请公布号 |
JPS57171962(A) |
申请公布日期 |
1982.10.22 |
申请号 |
JP19810216066 |
申请日期 |
1981.12.24 |
申请人 |
SHIGUMA TAU INDEYUSUTORIE FUARUMACHIYUCHIKE RIYUNICHI SPA |
发明人 |
MARIA ORUNERA CHINCHI;EMUMA KARESHIMA;PAORO DE BITSUTO |
分类号 |
A61K31/14;A01N37/14;A01N37/30;A61K;A61K31/095;A61K31/195;A61K31/205;A61K31/22;A61K31/265;A61P1/16;A61P17/00;A61P39/02;A61P43/00;C07C;C07C67/00;C07C313/00;C07C323/58;C07C325/00;C07C327/34 |
主分类号 |
A61K31/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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