发明名称 METHOD OF PREVENTING AND TREATING CEREBRAL INSUFFICIENCY USING CARBAMAZEPINE RELATED COMPOUNDS
摘要 The invention relates to a method of preventing or treating cerebral insufficiency, which method comprises administering to a human being in need of such treatment, orally or rectally, a prophylactic or a therapeutically effective amount of a compound of the general formula I <IMAGE> wherein X1 is hydrogen, halogen having an atomic number up to 35, or is cyano, and X2 and Y together are an additional bond, or X1 and X2 together are the oxo radical and Y is hydrogen, or X1 is hydroxy and X2 and Y are hydrogen. Examples of suitable compounds are 10,11-dihyro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide, 10,11-dihydro-10-oxo-5H-dibenz[b,f]azepine-5-carboxamide and, in particular, carbamazepine (5H-dibenz[b,f]azepine-5-carboxamide).
申请公布号 AU8263382(A) 申请公布日期 1982.10.21
申请号 AU19820082633 申请日期 1982.04.15
申请人 CIBA-GEIGY AG 发明人 CESARE MONDADORI
分类号 C07D223/28;A61K31/55;A61P25/28 主分类号 C07D223/28
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