NOVEAUX DERIVES DE L'ACIDE 4-PHENYL 4-OXO 2-BUTENOIQUE, LEURS SELS, LEUR PREPARATION LEUR APPLICATION COMME MEDICAMENTS ET LES COMPOSITIONS LES RENFERMANT

摘要

A compound of the formula I: (I) in which R1 and R2 in any position on the benzene ring are different from each other, and independently represent a hydroxy group or an alkoxy group containing from 1 to 8 carbon atoms, or else R1 and R2 together form an -OCH2CH2O-radical, and R represents a hydrogen atom or an alkyl group containing from 1 to 8 carbon atoms, as well as the alkali metal, alkaline earth metal, ammonium or amine salts of the said products of formula I in which R represents a hydrogen atom. These compounds have been found useful in the treatment of hyperchlorhydria, gastric and gastro-duodenal ulcers, gastritis, hiatal hernias, and gastric and gastro-duodenal ailments accompanied by gastric hyperacidity. Pharmaceutical compositions including these compounds are disclosed along with methods for their production.