Tri:methoxy phenacyl alkylamine(s) - having sedative, anti:depressant, and anti:aggressive activity

摘要

Trimethoxy phenacyl alkylamines of formula (I), and their acid addition salts are new. (where R = isopropyl or tert. butyl). In the pref. prepn. cpd. (II) is reacted with H2NR. (where X = C1 or Br). The maximum non-lethal dose (LDO) is between 250 and 500 mg/kg i.p. (mouse) Good sedative results have been obtained at a dosage of 10mg 3 times daily.