摘要 |
The present invention relates to a combination therapy of propane-1-sulfonic acid{3-[5-(4-chloro-phenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl-2,4-difluoro-phenyl]-amide}, or a pharmaceutically acceptable salt thereof, and an interferon for treating a patient suffering from a proliferative disorder, in particular a solid tumor, for example, colorectal cancer, melanoma, and thyroid cancer. In particular, the present invention relates to such a therapy wherein the interferon is peginterferon alfa-2a and the disorder is melanoma containing the V600E b-Raf mutation. |
申请人 |
F. Hoffmann La Roche AG |
发明人 |
DHINGRA, Kapil;HIGGINS, Brian;KOLINSKY, Kenneth;LEE, Richard J.;LESTINI, Brian;PACKMAN, Kathryn E.;SU, Fei |