| 发明名称 |
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| 摘要 |
<p>10-bromosandwicine and 10-bromoisosandwicine and acid addition salts thereof are disclosed. There novel compounds possess valuable pharmacological properties e.g. heart rhythm regulatory properties. Furthermore they are valuable intermediates for the preparation of 10-brominated Nb-quaternary sandwicine derivatives which exhibit heart rhythm regulatory and adrenolytic properties. 10-bromosandwicine is prepared by brominating sandwicine and can subsequently be isomerized into 10-bromoisosandwicine.</p> |
| 申请公布号 |
GR70381(B) |
申请公布日期 |
1982.10.04 |
| 申请号 |
GR19248001631 |
申请日期 |
1980.10.11 |
| 申请人 |
KALI-CHEMIE PHARMA GMBH |
发明人 |
DR. RER NAT WOLFGANG KEHRBACH;DR. RER NAT JOACHIM WEGENER |
| 分类号 |
C07D461/00;A61K31/435;A61K31/437;A61K31/4375;A61K31/475;A61P9/00;A61P9/06;C07D209/00;C07D221/00;C07D471/22 |
主分类号 |
C07D461/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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