发明名称 Aryl-oxazole derivs - anti-inflammatory agents
摘要 <p>(A) Pharmaceutical compositions comprising as active ingredient a compound of formula: (I) or an acid addition salt thereof. The 2-position contains one of the groups R' or R2; R' = opt. substd. aryl or heteroaryl; R2=saturated or olefinic aliphatic acid ( is not C2) or a salt, ester, amide or hydroxamic acid deriv. thereof; R3 = H, alkyl (C1-C4). (B) Compounds of formula I provided that when R' is unsubstd. phenyl in the 2-position and when R2 is n-propionic acid or acrylic acid residue in the 4-position, R3 in the 5-position is alkyl (C1-C4). Anti-inflammatory activity. beta-(4-phenyloxazol-2-yl) propionic acid.</p>
申请公布号 IT1060876(B) 申请公布日期 1982.09.30
申请号 IT19670022865 申请日期 1967.11.18
申请人 AMERICAN HOME PRODUCTS CORP 发明人
分类号 C07D277/44 主分类号 C07D277/44
代理机构 代理人
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