发明名称 |
Bicyclic prostaglandin analogs and method of synthesis |
摘要 |
New organopalladium reactions involving the addition of pi-allylpalladium compounds to strained bicyclic alkenes, and subsequent chain extension reactions employing the chemistry of organopalladium compounds are disclosed. By these techniques a large number of bicyclic prostaglandin analogs are prepared, which are useful as inhibitors of arachidonic acid induced platelet aggregation, and are specific inhibitors of thromboxane synthetase.
|
申请公布号 |
US4351949(A) |
申请公布日期 |
1982.09.28 |
申请号 |
US19810231596 |
申请日期 |
1981.02.05 |
申请人 |
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. |
发明人 |
LAROCK, RICHARD C. |
分类号 |
C07C405/00;(IPC1-7):C07C177/00 |
主分类号 |
C07C405/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|