摘要 |
<p>Pharmaceutically useful compounds are 5,6,7-trinor-4,8- inter-m-phenylene PGI<Sub>2</Sub> derivatives such as 5,6,7-trinor-4,8-inter-m-phenylene-13,14-didehydro PGI<Sub>2</Sub>, 5,6,7-trinor-4,8-inter-m-phenylene-16,16-dimethyl PGI<Sub>2</Sub>, 5,6,7-trinor-4,8-inter-m-phenylene-17-a-methyl-20-homo PGI<Sub>2</Sub>, 5,6,7-trinor-4,8-inter-m-phenylene-17,18,19,20-tetranor-16-phenoxy PGI<Sub>2</Sub>, 5,6,7-trinor-4,8-inter-m-phenylene-20-isopropylidene PGI<Sub>2</Sub>, 5,6,7-trinor-4,8-inter-(5-methyl-1,3-phenylene) PG1<Sub>2</Sub>, and 5,6,7-trinor-4,8-inter-m-phenylene-2,3-didehydro-16,17,18,19,20-pentanor-15-phenyl PGI<Sub>2</Sub>, and their pharmaceutical compositions.</p> |