发明名称 Process for the resolution of racemates and lactone esters used in said process.
摘要 <p>Racemic carboxylic acids are resolved into their enantiomers using optically active enantiomers of four lactones as resolving agents. The four lactones are 2,3-isopropylidene-ribonic acid-1,4-lactone; 1,2-isopropylidene-. glucofuranurono-3,6-lactone; 2-hydroxy-3,3-dimethyi-1,4- butyrolactone and 3,4-isopropylidene-arabino-1,5-lactone. Novel diastereoisomeric esters of the acids with the lactones are disclosed.</p>
申请公布号 EP0060445(A1) 申请公布日期 1982.09.22
申请号 EP19820101654 申请日期 1982.03.04
申请人 F. HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT 发明人 DUKE, COLIN, DR.;WELLS, ROBERT JOHN, DR.
分类号 C07C51/487;C07H19/01;(IPC1-7):07B19/00;07C51/353 主分类号 C07C51/487
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