摘要 |
PURPOSE:To detect the residual amount of ethylene oxide for sterilizing instruments and materials by coloration of an impregnated part, by covering a substrate having a part impregnated with 4-(4-nitrobenzyl)pyridine with a neutral plastic film having low gas permeability and good thermal adhesiveness. CONSTITUTION:About 0.05ml of a solution of 2-3% 4-(4-nitrobenzyl)-pyridine in a solvent such as ethanol, ethyl acetate or acetone is applied to the center of a piece of filter paper or other paper that has high ink permeability and air-dried. Next, the entire paper is covered by a 5-40mu thick, neutral plastic film (polyvinyl alcohol, nylon, etc.) that has low gas permeability and high thermal adhesiveness, or by a laminated film consisting of a plastic (polyethylene, polypropylene, etc.) that has high gas permeability and good thermal adhesiveness as its internal layer and the above-mentioned film that has low gas permeability as its external layer. This test paper is placed in a sterilizing device together with instruments and materials to be sterilized by ethylene oxide (EO), and EO is removed until the color corresponding to an appropriate amount of residual EO is obtained, observing changes in color of colorless impregnated part of the filter paper due to residual EO. |