| 摘要 |
Compounds of the formula <IMAGE> wherein one of the double bonds indicated by broken lines is present in 4,5 or 5,6-position, R is hydrogen or lower alkyl, R<1> is methyl, hydrogen or hydroxy; R<2> is hydrogen, methyl or fluoro; and R<21> is hydrogen, fluoro, trifluoromethyl or methyl; with the proviso that when R<21> is trifluoromethyl, R<2> is hydrogen or methyl, their pharmaceutically acceptable salts, optical antipodes or racemates are useful as anti-secretory agents, anti-hypertensives, anti-ulcerogenic agents and blood platelet aggregation inhibiting agents. |
