摘要 |
A method for the manufacture of commercially useful alpha-halo and alpha-dihalo ketones and aldehydes from alkynes by enzymatic reaction. The method avoids the use of free halogen, permits control of the ratio of alpha-halo product to alpha-dihalo product and offers the possibility of economic utilization of coal as a raw feedstock in many industrial applications. In the method an alkyne is acted upon in a reaction mixture also comprising a halogenating enzyme, an oxidising agent, and a halide ion source. |