Water-in-oil emulsion for use in the potentation of the immune system of animals.

摘要

Intraperitoneal injection of animals with antigen-free water-in-oil emulsions comprising an aqueous phase dispersed in a mineral oil by means of an emulsifier was found to induce an immunological response improving the mucosal immunity of the animals. The invention relates to these water-in-oil emulsions for use in the immunization of animals by intraperitoneal injection, as well as to antigen-free injectable pharmaceutical water-in-mineral oil emulsions in which the emulsifier is a mixture of at least one sorbitan fatty acid ester, preferably sorbitan trioleate, and at least one polyoxyethylene sorbitan fatty acid ester, preferably polyoxyethylene-20-sorbitan trioleate.