摘要 |
<p>10,875-C-1 ANALYTICAL OR CLINICAL ISOCYANATES DERIVATIVES Novel isocyanates such as, for example, blocked L-tyrosine methyl ester isocyanate, are reacted with compounds of biological, clinical interest or the like such as, for example, digoxin, to form derivatives respective to tagging, as by radiolabeling. The tagged derivatives may then be employed to determine the presence of a compound of interest in nanomolar or even picomolar amounts by using clinical analysis techniques such as radioimmunoassay. RELATED APPLICATION Hedaya and Theodoropulos, Canadian application Serial No. 278,460, for: A Method Of Preparing Halosilyl Carbamates And Isocyanates Derived Therefrom, filed on May 16, 1977. SPECIFICATION</p> |