摘要 |
Title title compds. (I; R1 = benzyl, or alkyl-, halogen-, hydroxyl-, or nitro- group substituted benzyl; R2 = 1-piperidino) useful as blood pressure lowering agent, were prepd. by reaction of 2,3-dihydropyran(II) with hydroxylamine. Thus, 16.7 g hydroxylamine chloric acid salt and 23.6g potassium acetate was melted in 540ml acetic acid and reacted with 16.3 g 3-benzyl-6-methyl-2-(1-piperidino)-3,4-dihydro-2H-pyran to give 5-benzyl-2-methylpiperidine.
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