发明名称 |
DERIVATIVES OF ANTIBIOTIC XK-62-2 AND METHOD OF PRODUCTION THEREOF |
摘要 |
Acylation of the antibiotic which is known under the name XK-62-2 and has the formula A <IMAGE> in which R6 is hydrogen with a compound of the formula Y1Y2N-CH2-CH2-CHOH-COZ initially results in a mixture of various acylated compounds from which the required compound with the group <IMAGE> is isolated, and the protective group Y2 is removed before or after the isolation. The antibiotic has a broad spectrum of antibacterial activity, especially against Escherichia coli KY 8327 and 8348. |
申请公布号 |
PH15160(A) |
申请公布日期 |
1982.08.27 |
申请号 |
PH19090000166 |
申请日期 |
1974.12.11 |
申请人 |
ABBOTT LAB |
发明人 |
KUNIKATSU SHIRAHATA;SHINJI TOMIOKA;TAKASHI NARA;HIDEO MATSUSHIMA;ISAO MATSUBARA |
分类号 |
A61K31/70;A61K31/7028;A61K31/7034;A61K31/7036;A61P31/04;B01J23/00;B01J25/00;C07B61/00;C07H15/236 |
主分类号 |
A61K31/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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