AZETIDINE DERIVATIVES

摘要

AZETIDINE DERIVATIVES Azetidine derivatives of the formula: wherein A is amino or substituted amino; COB is carboxy or protected carboxy; R1 is =C(CH3)2, , or (R4 is alkyl, aryl or aralkyl); OR2 and OR3 independently or taken together with each other represent a ketal; Y is hydrogen or methoxy; Z is hydrogen or halogen! and a process for preparation thereof. Used as intermediates in the preparation of potent antimicrobials l-oxadethiacephalosporins.