PROCEDIMIENTO DE PREPARAR DERIVADOS DEL ACIDO NICOTINICO

摘要

The novel derivatives of the nicotinic acid, having general formula: …… wherein R1 is H or methyl and R2 and R3, when separated, respectively represent OH and CH2OH, or are combined in a cyclic structure forming the group: …… show analgesic and anti-inflammatory activity associated with specific effects, or hypoglycemic and hypochlolesteremic activity. The subject derivatives are prepared by reacting (3-4) isopropyliden pyridoxine with the chloride of the nicotinic acid.