PURIFIED PROTEINS AND PROCESS THEREFOR

摘要

EV 4100/12 A process for purifying proteins having molecular weights greater than 12,000, such as interferon, which process comprises passing an aqueous solution of said protein in an impure state through a buffer equilibrated column of a modified porous silica matrix under high performance liquid chromatography conditions and eluting said protein with an increasing or decreasing gradient of an aqueous water miscible solvent.