| 摘要 |
<p>A nuclease resitant hydrophilic complex of polyriboinosinic-polyribocytidylic acid, poly-1-lysine and carboxymethycellulose, wherein the nucleotide homopolymers have sedimentation coefficients of 4S and each homopolymer has a molecular weight of about 25,000 or less. When administered in a pharmacologically acceptable aqueous carrier, such as a saline solution, the complex is effective in inducing the synthesis of antiviral levels of interferon in the host, while modulating the toxicity reactions normally associated with the administration of greater molecular weight complexes of polyriboinosinic-polyribocytidylic acid, particularly hypotension.</p> |
