发明名称 Radiolabelled substrates for assaying mammalian enzymes.
摘要 <p>Compounds which are substrates for mammalian enzymes, especially proteolytic and peptidase enzymes, are disclosed. These compounds, in general, have the general formula X-T, W-Y or X-(Pep)-Y, wherein X is a radiolabelled benzoyl or hydroxyphenylpropanoyl group, T is the -NH residue of a known chromogenic or fluorogenic substrate comprising at least one amino acid group which may be substituted with other organic groups, Y is a radiolabelled benzylamine group, W is the . &lt;Chemistry id="chema01" num="0001"&gt;&lt;Image id="ia01" he="14" wi="18" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /&gt;&lt;/Chemistry&gt;residue of a known chromogenic or fluorogenic substrate comprising at least one amino acid group which may be substituted with other organic groups, and (Pep) is a difunctional or polyfunctional residue from a known chromogenic or fluorogenic substrate comprising at least two amino acid groups in peptide linkage, which residue may be substituted with other organic groups.</p>
申请公布号 EP0056015(A1) 申请公布日期 1982.07.14
申请号 EP19820300047 申请日期 1982.01.06
申请人 RYAN, JAMES WALTER 发明人 RYAN, JAMES WALTER;CHUNG, ALFRED
分类号 C07K5/083;C07K5/087;C07K5/097;C07K7/06;C12Q1/37;(IPC1-7):12Q1/34;01N33/60 主分类号 C07K5/083
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