4,1-BENZOXAZEPINES AND THIA ANALOGUES THEREOF

摘要

4,1-BENZOXAZEPINES AND THIA ANALOGS THEREOF 4,1-Benzoxazepines and thia analogs thereof of the formula: (wherein -A-B- is the following group; , or (wherein R1 is hydrogen, C1 to C3 alkyl, or C7 to C9 aralkyl; R2 is C1 to C3 alkyl or C1 to C3 .alpha.-aminoalkyl; R3 is C2 to C6 dialkylamino; R4 is C2 to C6 dialkylamino or C5 to C7 alkylpiperazino; R5 is C1 to C3 alkyl; and Q is oxygen or sulfur); D is oxygen or sulfur; X is halogen or nitro; Y is hydrogen or halogen; and Z is hydrogen, C1 to C3 alkoxy, or C3 to C9 dialkylaminoalkoxy; with proviso that when -A-B- is , Z is not hydrogen). being useful as novel central nervous system drugs are prepared in various synthetic routes.