ATTENUATED STRAIN OF FELINE INFECTIOUS PERITONITIS VIRUS, METHOD FOR PREPARING IT AND VACCINE COMPRISING IT

摘要

Feline infectious peritonitis is a disease of members of the genus Felix which is almost invariably fatal, and for which there is currently no vaccine available. Indeed many attempts to isolate and grow the virus have failed. By passaging a virulent isolate of feline infectious peritonitis (FIP) virus in feline embryonic cell cultures about 100 times an attenuated strain of FIP virus can be produced which stimulates the production of antibody in susceptible animals without causing overt disease. Such an attenuated strain can be formulated into a vaccine for administrative purposes.