发明名称 |
DERIVATIVES OF 1-PHENYL-1-PROPANOL |
摘要 |
<p>A derivative of 1-phenyl-1-propanol of the general formula I : (I) wherein :(a) R1 represents hydrogen, an linear or ramified alkylthio (c1-C3), linear or ramified alkylsulfinyl (C1-C3), linear or ramified alkylsulfonyl (C1-C3) or mercapto radical ;(b) R2 represents : b-1 a hydroxy radical ; b-2 an oxo-2-pyrrolidinyl-1 radical which may bc subs tituted by a hydroxy group ; b-3 a NHR3 radical wherein R3 represents : - hydrogen- a linear or ramified alkyl (C6-C16) radical or a linear alkyl (C2-C4) radical substituted by a phenyl or phenoxy group, with the proviso that R1 is not an alkylthio radical- a linear or ramified alkyl (C1-C7) radical substi tuted by a lower carboxy or carbalkoxy (C1-C3) group in the position ; as well as non toxic and pharmaceutically acceptable salts and esters of these derivatives.</p> |
申请公布号 |
CA1127164(A) |
申请公布日期 |
1982.07.06 |
申请号 |
CA19790331500 |
申请日期 |
1979.07.10 |
申请人 |
CONTINENTAL PHARMA |
发明人 |
LAMBELIN, GEORGES;RONCUCCI, ROMEO;ROBA, JOSEPH;GILLET, CLAUDE |
分类号 |
A61K31/045;A61K31/10;A61K31/135;A61K31/195;A61K31/215;A61K31/22;A61K31/40;A61K31/4015;A61P9/00;C07C67/00;C07C213/00;C07C215/30;C07C217/16;C07C219/22;C07C229/14;C07C313/00;C07C315/04;C07C317/32;C07C323/19;C07C323/32;C07D207/26;C07D207/27;C07D207/277;C07D303/34;(IPC1-7):07C147/00;07C149/32;07D207/27 |
主分类号 |
A61K31/045 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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