摘要 |
D-L carnitine is converted into D,L- carnitine acid chloride by treating it, without previously protecting the hydroxyl group, with a halogenating agent at room temperature for a reaction period comprised between 1.5 hours and 12 hours. If the foregoing reaction conditions are not strictly complied with, a sharp decrease in the yield and the formation of by-products, primarily crotonylbetaine, will take place. |