发明名称 PHARMACEUTICAL SALTS OF 4'-(9-ACRIDINYLAMINO)METHANESULFON-M-ANISIDIDE
摘要 For use as, inter alia, an anti-neoplastic agent, there is disclosed a compound of the formula:- <CHEM> wherein X is an acid having a total of from three to six carbon atoms, two to five hydroxy groups and an acidic group selected from -CO2H and -OPO3H2 with the proviso that, when the total number of carbon atoms is three or four, the acidic group is -OPO3H2. These particular salts of 4 min -(9-acridinylamino)methanesulfon-m-anisidide remain in solution for a reasonable period and hence permit the use of the compound in this salt form for introduction into a mammal. Also disclosed are the processes for producing the salts and pharmaceutical compositions including the salts.
申请公布号 ZA8101304(B) 申请公布日期 1982.06.30
申请号 ZA19810001304 申请日期 1981.02.06
申请人 WARNER LAMBERT CO 发明人 FISHER JAMES R;KULIER CHARLES P
分类号 C07D219/12;A61K9/08;A61K9/14;A61K9/48;A61K31/00;A61P31/04;A61P31/12;A61P35/00;C07C59/245;C07D219/10;C07F9/09;C07F9/113;C07H7/027;C07H7/033 主分类号 C07D219/12
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