Novel halogenated prostacyclins, process for the production thereof, and pharmaceutical use thereof.

摘要

Novel 5- or 7-monohalogenated or 5,7-dihalogenated -PGI<Sub>1</Sub> and 5- or 7-monohalogenated or dihalogenated PGI<Sub>2</Sub> (except 5-monofluorinated PGI<Sub>2</Sub>). The novel halogenated prostacyclins are useful for controlling vascular actions and inhibiting metastasis of a malignant tumor, and also in organ transplantation, extracorporeal circulation and the like. The present invention also provides processes for preparing the novel halogenated prostacyclins.